EN The value of preoperative s-CEA level as an independent prognostic indicator is unclear. But many have been reported that preoperative s-CEA levels were correlated with the extent of tumor burden, tumor size, Dukes' stage, depth of invasion
and
survival of patient.
In this study, we obained survival curves according to preoperative s-CEA level in colon and rectal cancer and analyzed correlation between preoperative s-CEA levels and pathologic features.
Four hundred ninty three patients who had operations for colorectal cancer at SNUH from 1979 to 1986 were studied and the analyzed pathologic features were cell differentiation, size of tumor, depth of invasion, number of involved lymph nodes and
Dukes'
stage.
In colon cancer, there was no correlation between preoperative s-CEA levels and five year survival rates and preoperative s-CEA levels were correlated with extent of nodal metastasis and stage of disease. In rectal cancer, elevated preoperative
s-CEA
levels were associated with poor survival rate(p<0.05) and preoperative s-CEA levels were correlated with size of tumor, depth of invasion, extent of nodal metastasis and of disease.
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